I think we all at some point feel like we want to give up. With me, I tend to find the combination of travel and photography a double edged sword. On one side it is exciting, adventurous and when the good images happen, I get a real sense of satisfaction.
But when things aren't working out, I can reach a real low point.
Waiting for days for cloud to clear, or for the rain to stop can be soul destroying. I'll try anything to take my mind of it - try to read a good book, talk to fellow travelers that I meet. But because of the displacement, I feel like an outsider and the fact that the photography isn't working out the way I wanted it to - just seems to cement the idea that I shouldn't have come in the first place.
I know that deep down, these feelings are inevitable. If you really care about what you do, and strive to create something that really means a lot to you, you can't be flippant about it. You have to accept that along with the highs, there will be lows too.
That's just part and parcel of the art of Photography.